PCBP1 rabbit pAb
This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. Th
Product Specifications
Background
Gene ID
5093
UniProt
Q15365
Cellular Locus
Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
39kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9064-1.pdf
Observed Molecular Weight
39 kD
Subcellular Location
Nucleus. Cytoplasm. Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm.
Gene ID (Human)
5093
SwissProt (Human)
Q15365
Available Sizes
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