BCL3 rabbit pAb
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Gene ID
602
UniProt
P20749
Cellular Locus
Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation..
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,Goat
Reactivity
Human; Rat; Mouse; ; Goat
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IHC, IF, WB
Validated Applications
IHC,IF,WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
49kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES9000-1.pdf
Observed Molecular Weight
49 kD
Subcellular Location
Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .
Gene ID (Human)
602
SwissProt (Human)
P20749
Available Sizes
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