Mcl1-IN-14
Mcl1-IN-14 (compound 5) is a reversible covalent inhibitor of Mcl-1 with the activity of inhibiting Mcl-1. Mcl1-IN-14 covalently targets the non-catalytic lysine side chain of Mcl-1 and has higher potency than non-covalent counterparts, which can be used to develop Mcl-1 inhibitory compounds and study related biological phenomena.
Product Specifications
CAS Number
2012563-29-8
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Smiles
O=C(O)C(NC1=C2C=CC=C1C3=C(N(N=C3COC4=CC=C(C(C=O)=C4)B(O)O)C)C)=C2CCCOC5=C6C=CC=CC6=CC=C5
Molecular Formula
C35H32BN3O7
Molecular Weight
617.46
References & Citations
[1]Inhibition of Mcl-1 through covalent modification of a noncatalytic lysine side chain
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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