ATX3 rabbit pAb
Ataxin 3 (ATXN3) Homo sapiens Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2016],
Product Specifications
Background
UniProt
P54252
Swiss Prot
P54252
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 200-280
Target
Ataxin-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Nucleus matrix . Nucleus . Predominantly nuclear, but not exclusively, inner nuclear matrix.
Gene ID (Human)
4287
Available Sizes
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