Elastase-IN-3

Elastase-IN-3 (Compound 2i) is an Elastase inhibitor of Pseudomonas aeruginosa. Elastase-IN-3 inhibits the quorum sensing system of Pseudomonas aeruginosa by targeting the LasR protein (KD value of 7.04 M), thereby preventing food spoilage caused by Pseudomonas aeruginosa[1].

Product Specifications

CAS Number

[15015-57-3]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Antibiotic; Bacterial; Elastase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/elastase-in-3.html

Purity

99.71

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1SSC2=CC=C(O)C=C2

Molecular Formula

C12H10O2S2

Molecular Weight

250.34

Precautions

H315, H319

References & Citations

[1]Zhang ZS, et al. Structure-Based Discovery of Symmetric Disulfides from Garlic Extract as Pseudomonas aeruginosa Quorum Sensing Inhibitors. J Agric Food Chem. 2024 Sep 4.