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MOT4 rabbit pAb

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al. 1998 [PubMed 9425115]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]) .[supplied by OMIM, Mar 2008]

Product Name Alternative

Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)

UniProt

O15427

Swiss Prot

O15427

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human MOT4 Polyclonal

Target

MOT4

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Molecular Weight

50kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

50kD

Fragment

IgG

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Other Product Names

Monocarboxylate transporter 4 (MCT 4) (Solute carrier family 16 member 3)

Gene ID (Human)

9123

Available Sizes

Curated Selection

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