PEK/PERK rabbit pAb
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Product Specifications
Background
Product Name Alternative
UniProt
Q9NZJ5
Swiss Prot
Q9NZJ5
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PEK/PERK Polyclonal
Target
PERK
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
130kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
130kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Other Product Names
Gene ID (Human)
9451
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![[3- (1-Benzyl-1H-1,3-benzimidazol-2-yl) -1H-pyrazol-1-yl] (4-iodophenyl) methanone](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
[3- (1-Benzyl-1H-1,3-benzimidazol-2-yl) -1H-pyrazol-1-yl] (4-iodophenyl) methanone
[3- (1-Benzyl-1H-1,3-benzimidazol-2-yl) -1H-pyrazol-1-yl] (4-iodophenyl) methanone
Bovine Taste Receptor Type 2 Member 14 (TAS2R14) ELISA Kit
Canine Transcription factor SOX 21 (SOX21) ELISA Kit
Rdh1 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)