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OASL rabbit pAb

Caution: This may not be the true ortholog of mouse OASL. function: Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA. induction: By interferons. similarity: Belongs to the 2-5A synthetase family. similarity: Contains 2 ubiquitin-like domains. subunit: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1. tissue specificity: Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.

Product Specifications

Background

Caution:This may not be the true ortholog of mouse OASL., function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA., induction:By interferons., similarity:Belongs to the 2-5A synthetase family., similarity:Contains 2 ubiquitin-like domains., subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR) . TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1., tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.

Synonyms

2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)

Gene ID

8638

UniProt

Q15646

Cellular Locus

[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human OASL. at AA range: 1-50

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight

60kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8870-1.pdf

Observed Molecular Weight

60 kD

Subcellular Location

[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.

Other Product Names

2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)

Gene ID (Human)

8638

SwissProt (Human)

Q15646

Available Sizes

Curated Selection

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