COL8A2 rabbit pAb
This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],
Product Specifications
Background
Synonyms
Collagen alpha-2(VIII) chain (Endothelial collagen)
Gene ID
1296
UniProt
P25067
Cellular Locus
Secreted, extracellular space, extracellular matrix, basement membrane.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human COL8A2. at AA range: 611-660
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Molecular Weight
80kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8857-1.pdf
Observed Molecular Weight
80 kD
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Other Product Names
Collagen alpha-2 (VIII) chain (Endothelial collagen)
Gene ID (Human)
1296
SwissProt (Human)
P25067
Available Sizes
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