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COL8A2 rabbit pAb

This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014],

Product Specifications

Background

This gene encodes the alpha 2 chain of type VIII collagen. This protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Product Name Alternative

Collagen alpha-2 (VIII) chain (Endothelial collagen)

UniProt

P25067

Swiss Prot

P25067

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human COL8A2. at AA range: 611-660

Target

COL8A2

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Buffer

-20°C/1 year

Molecular Weight

80kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

80kD

Fragment

IgG

Subcellular Location

Secreted, extracellular space, extracellular matrix, basement membrane.

Other Product Names

Collagen alpha-2 (VIII) chain (Endothelial collagen)

Gene ID (Human)

1296

Available Sizes

Curated Selection

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