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Parafibromin rabbit pAb

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],

Product Specifications

Background

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]

Product Name Alternative

Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)

UniProt

Q6P1J9

Swiss Prot

Q6P1J9

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human Parafibromin. at AA range: 51-100

Target

Parafibromin

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Buffer

-20°C/1 year

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

60kD

Fragment

IgG

Subcellular Location

Nucleus .

Other Product Names

Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)

Gene ID (Human)

79577

Available Sizes

Curated Selection

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