LIM and SH3 domain protein 1 rabbit pAb
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],
Product Specifications
Background
Synonyms
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene ID
3927
UniProt
Q14847
Cellular Locus
Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Associated with the F-actin rich cortical cytoskeleton..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
38kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8817-1.pdf
Observed Molecular Weight
38 kD
Subcellular Location
Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .
Other Product Names
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene ID (Human)
3927
SwissProt (Human)
Q14847
Available Sizes
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