LIM and SH3 domain protein 1 rabbit pAb
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],
Product Specifications
Background
Product Name Alternative
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
UniProt
Q14847
Swiss Prot
Q14847
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human LIM and SH3 domain protein 1. at AA range: 90-130
Target
LIM and SH3 domain protein 1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .
Other Product Names
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene ID (Human)
3927
Available Sizes
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