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AVP Receptor V3 rabbit pAb

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008]

Synonyms

Vasopressin V1b receptor (V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor)

Gene ID

553

UniProt

P47901

Cellular Locus

Cell membrane ; Multi-pass membrane protein.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, ELISA

Validated Applications

IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8759-1.pdf

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

Vasopressin V1b receptor (V1bR; AVPR V1b; AVPR V3; Antidiuretic hormone receptor 1b; Vasopressin V3 receptor)

Gene ID (Human)

553

SwissProt (Human)

P47901

Available Sizes

Curated Selection

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