PACAP rabbit pAb

Function: May be involved in regulation of apoptosis. induction: Down-regulated in primary B-cells early after ligand-stimulated activation. subcellular location: In (PubMed: 11350957) diffuse granular localization in the cytoplasm surrounding the nucleus. subunit: Isoform 2 interacts with CASP2 and CASP9. tissue specificity: Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

Product Specifications

Background

Function:May be involved in regulation of apoptosis., induction:Down-regulated in primary B-cells early after ligand-stimulated activation., subcellular location:In (PubMed:11350957) diffuse granular localization in the cytoplasm surrounding the nucleus., subunit:Isoform 2 interacts with CASP2 and CASP9., tissue specificity:Widely expressed with highest levels in adult brain. Expression is frequently lower in intestinal-type gastric cancer.

UniProt

Q8WU39

Swiss Prot

Q8WU39

Reactivity

Human; Rat; Mouse

Immunogen

Synthetic peptide from human protein at AA range: 1-50

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

[Isoform 1]: Endoplasmic reticulum lumen . Secreted .; [Isoform 2]: Cytoplasm . Diffuse granular localization in the cytoplasm surrounding the nucleus (PubMed:11350957) .