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Mouse IGF-II Protein, His tag (Animal-Free)

Mouse Insulin Like Growth Factors 2 (IGF-II) is a 7.34 kDa member of the Insulin-like Growth Factors with 67 amino acid residues. IGF-II is mainly expressed from early embryonic somatic tissues, liver, and epithelial cells lining the surface of the brain. IGF-II is mediating the embryonic development and placental growth, while also promoting tumor growth. IGF-II affects regulation of cell proliferation, growth, migration, differentiation and survival via binding to IGF-I receptor.

Product Specifications

Background

Mouse Insulin Like Growth Factors 2 (IGF-II) is a member of the Insulin-like Growth Factors. IGF-II is mainly expressed from early embryonic somatic tissues, liver, and epithelial cells lining the surface of the brain. IGF-II is mediating the embryonic development and placental growth, while also promoting tumor growth. IGF-II affects regulation of cell proliferation, growth, migration, differentiation and survival via binding to IGF-I receptor.

Product Name Alternative

AL033362, Igf-2, M6pr, Mpr, Peg, Peg2

Accession Number

P09535

Tag

IGF-II

Type

Cytokines and proteins

Applications

His tag

Purity

>98% as determined by SDS-PAGE.

Activity

Measured by its ability to induce MCF-7 cells proliferation.The ED50 for this effect is <6 ng/mL

Molecular Weight

8.20 kDa

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Features & Benefits

Endotoxin: <0.1 EU per 1 μg of the protein by the LAL method.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Please store the whole kit at -20°C upon receipt , and protect from light. The kit is valid for 24 months. Please refer to the table below Materials supplied and Storage conditions to store all the components.

Protein Length

The recombinant Mouse IGF-II Protein consists of 67 amino acids and predicts a molecular mass of 8.20 kDa

Formulation

Lyophilized from PBS, pH 8.0

Applications Notes

Mouse

Other Product Names

AL033362, Igf-2, M6pr, Mpr, Peg, Peg2

Recommended Usage

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously

Preparation

E. coli

AA Sequence

Amino acid sequence derived from Mouse IGF-II Protein (Ala25-Glu91) (P09535) was expressed with 6xHis tag at the N-terminus

Available Sizes

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