IL-27A rabbit pAb
The protein encoded by this gene is one of the subunits of a heterodimeric Cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this Cytokine are mediated by the class I Cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q8NEV9
Swiss Prot
Q8NEV9
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 1-50
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted . Does not seem to be secreted without coexpression of EBI3.
Other Product Names
Interleukin-27 subunit alpha (IL-27 subunit alpha; IL-27-A; IL27-A; p28)
Gene ID (Human)
246778
Available Sizes
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