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IL-19 rabbit pAb

The protein encoded by this gene is a Cytokine that belongs to the IL10 Cytokine subfamily. This Cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar Cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this Cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3) . A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Synonyms

Interleukin-19 (IL-19;Melanoma differentiation-associated protein-like protein;NG.1)

Gene ID

29949

UniProt

Q9UHD0

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Rat

Reactivity

Human; Rat

Immunogen

Synthetic peptide from human protein at AA range: 51-100

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000

Molecular Weight

20kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8710-1.pdf

Observed Molecular Weight

20 kD

Subcellular Location

Secreted.

Other Product Names

Interleukin-19 (IL-19; Melanoma differentiation-associated protein-like protein; NG.1)

Gene ID (Human)

29949

SwissProt (Human)

Q9UHD0

Available Sizes

Curated Selection

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