PDGF-C rabbit pAb

Platelet derived growth factor C (PDGFC) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010],

Product Specifications

Background

UniProt

Q9NRA1

Swiss Prot

Q9NRA1

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide from human protein at AA range: 61-110

Clonality

Polyclonal

Source

Rabbit

Applications

IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm, cytosol . Secreted . Nucleus . Cytoplasmic granule . Cell membrane . Sumoylated form is predominant in the nucleus (PubMed:15247255) . Stored in alpha granules in platelets (PubMed:15061151) . .

Other Product Names

Platelet-derived growth factor C (PDGF-C; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form) ; Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form) ]