PD-L2 rabbit pAb
Function: Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and Cytokine production. induction: Up-regulated by IFNG stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL4. similarity: Belongs to the immunoglobulin superfamily. BTN/MOG family. similarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain. similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain. subunit: Interacts with PDCD1. tissue specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
Product Specifications
Background
UniProt
Q9BQ51
Swiss Prot
Q9BQ51
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 31-80
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, IHC-p 1:50-200, ELISA 1:10000-20000
Molecular Weight
30kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8685-1.pdf
Observed Molecular Weight
30kD
Fragment
IgG
Subcellular Location
Other Product Names
Programmed cell death 1 ligand 2 (PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; Butyrophilin B7-DC; B7-DC; CD antigen CD273)
Gene ID (Human)
80380
Available Sizes
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