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ASCL1 rabbit pAb

Achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]

Synonyms

Achaete-scute homolog 1 (ASH-1;hASH1;Class A basic helix-loop-helix protein 46;bHLHa46)

Gene ID

429

UniProt

P50553

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide from human protein at AA range: 190-236

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

IHC, IF, ELISA

Validated Applications

IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

IHC-p 1:50-200, ELISA 1:10000-20000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8645-1.pdf

Subcellular Location

Nucleus .

Other Product Names

Achaete-scute homolog 1 (ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46)

Gene ID (Human)

429

SwissProt (Human)

P50553

Available Sizes

Curated Selection

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