ASCL1 rabbit pAb
Achaete-scute family bHLH transcription factor 1 (ASCL1) Homo sapiens This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
P50553
Swiss Prot
P50553
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 190-236
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
Achaete-scute homolog 1 (ASH-1; hASH1; Class A basic helix-loop-helix protein 46; bHLHa46)
Gene ID (Human)
429
Available Sizes
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