ASIC1 rabbit pAb
This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],
Product Specifications
Background
Synonyms
Acid-sensing ion channel 1 (ASIC1;Amiloride-sensitive cation channel 2, neuronal;Brain sodium channel 2;BNaC2)
Gene ID
41
UniProt
P78348
Cellular Locus
Cell membrane ; Multi-pass membrane protein. Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity)..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 220-280
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, IHC-f, ELISA
Validated Applications
WB,IHC,IF,IHC-f,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Molecular Weight
55kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8643-1.pdf
Observed Molecular Weight
55 kD
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity) . .
Other Product Names
Acid-sensing ion channel 1 (ASIC1; Amiloride-sensitive cation channel 2, neuronal; Brain sodium channel 2; BNaC2)
Gene ID (Human)
41
SwissProt (Human)
P78348
Available Sizes
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