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IL-31 rabbit pAb

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al. 2004 [PubMed 15184896]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]) .[supplied by OMIM, Mar 2008]

Product Name Alternative

Interleukin-31 (IL-31)

UniProt

Q6EBC2

Swiss Prot

Q6EBC2

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IL31. AA range:21-70

Target

IL-31

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

Buffer

-20°C/1 year

Molecular Weight

65kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

65kD

Fragment

IgG

Subcellular Location

Secreted .

Other Product Names

Interleukin-31 (IL-31)

Gene ID (Human)

386653

Available Sizes

Curated Selection

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