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IL-31 rabbit pAb

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al. 2004 [PubMed 15184896]). [supplied by OMIM, Mar 2008],

Product Specifications

Background

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]) .[supplied by OMIM, Mar 2008]

Synonyms

Interleukin-31 (IL-31)

Gene ID

386653

UniProt

Q6EBC2

Cellular Locus

Secreted.

Host

Rabbit

Species Reactivity

Human,Rat,Mouse,

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IL31. AA range:21-70

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC, IF, ELISA

Validated Applications

WB,IHC,IF,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

Molecular Weight

65kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8589-1.pdf

Observed Molecular Weight

65 kD

Subcellular Location

Secreted .

Other Product Names

Interleukin-31 (IL-31)

Gene ID (Human)

386653

SwissProt (Human)

Q6EBC2

Available Sizes

Curated Selection

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