IRS2 rabbit pAb
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
IRS2
Gene ID
8660
UniProt
Q9Y4H2
Cellular Locus
Cytoplasm, cytosol.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 660-700
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Molecular Weight
170kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8554-1.pdf
Observed Molecular Weight
170 kD
Subcellular Location
Cytoplasm, cytosol .
Other Product Names
IRS2
Gene ID (Human)
8660
SwissProt (Human)
Q9Y4H2
Available Sizes
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