FAM48A rabbit pAb
Function: Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by Fgf signaling and Snail. similarity: Belongs to the FAM48 family. subunit: Interacts with MAPK14. tissue specificity: Highly expressed in testis, moderately in brain and pituitary gland. Expressed in several fetal tissues, including lung, brain, thymus and kidney. Expression is down-regulated in malignant prostate tissues.
Product Specifications
Background
UniProt
Q8NEM7
Swiss Prot
Q8NEM7
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human FAM48A. AA range:231-280
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8546-1.pdf
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
FAM48A C13orf19 FP757
Gene ID (Human)
55578
Available Sizes
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