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Cytokeratin 14/17 rabbit pAb

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008],

Product Specifications

Background

This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11. [provided by RefSeq, Jul 2008]

Synonyms

KRT14

Gene ID

3861

UniProt

P02533/Q04695

Cellular Locus

Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic peptide from human protein at AA range: 261-310

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, ELISA

Validated Applications

WB,ELISA

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight

52kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8537-1.pdf

Observed Molecular Weight

52 kD

Subcellular Location

Cytoplasm. Nucleus. Expressed in both as a filamentous pattern.

Other Product Names

KRT14

Gene ID (Human)

3861

SwissProt (Human)

P02533/Q04695

Available Sizes

Curated Selection

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