RCC1 rabbit pAb
Disease: Patients with Raynaud disease produce antibodies that bind to RCC1. function: Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. similarity: Contains 7 RCC1 repeats. subcellular location: Becomes dispersed throughout the cytoplasm during mitosis.
Product Specifications
Background
Synonyms
RCC1 CHC1
Gene ID
1104
UniProt
P18754
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 301-350
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000
Molecular Weight
45kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8532-1.pdf
Observed Molecular Weight
45 kD
Subcellular Location
Other Product Names
RCC1 CHC1
Gene ID (Human)
1104
SwissProt (Human)
P18754
Available Sizes
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