C8 β rabbit pAb
This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
Product Specifications
Background
Product Name Alternative
Complement component C8 beta chain (Complement component 8 subunit beta)
UniProt
P07358
Swiss Prot
P07358
Reactivity
Human; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420
Target
C8 β
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
70kD
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
Complement component C8 beta chain (Complement component 8 subunit beta)
Gene ID (Human)
732
Available Sizes
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