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GABARAP rabbit pAb

Function: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the MAP1 LC3 family. subunit: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1. tissue specificity: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.

Product Specifications

Background

Function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the MAP1 LC3 family., subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity) . Interacts with ULK1., tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.

Product Name Alternative

GABA (A) receptor-associated protein-like 2

UniProt

P60520

Swiss Prot

P60520

Reactivity

Human; Mouse; Rat

Immunogen

Synthetic Peptide of GABARAP AA range: 26-75

Target

GABARAP

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Buffer

-20°C/1 year

Molecular Weight

17kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

17kD

Fragment

IgG

Subcellular Location

Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum membrane . Golgi apparatus .

Other Product Names

GABA (A) receptor-associated protein-like 2

Gene ID (Human)

11345

Available Sizes

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