PI 3 Kinase Class 3 rabbit pAb
Catalytic activity: ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate. Cofactor: Manganese. function: Catalytic subunit of the PI3K complex. Involved in the transport of lysosomal enzyme precursors to lysosomes. similarity: Belongs to the PI3/PI4-kinase family. similarity: Contains 1 PI3K/PI4K domain. subunit: Probably forms a complex with AMBRA1 and BECN1 (By similarity). Heterodimer. This subunit, part of a complex composed of regulatory and catalytic subunits, associates with regulatory subunit PIK3R4. tissue specificity: Ubiquitously expressed, with a highest expression in skeletal muscle.
Product Specifications
Background
Synonyms
phosphoinositide-3-kinase, class 3
Gene ID
5289
UniProt
Q8NEB9
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse,Rat,Predicted:Cow:PIG
Reactivity
Human; Mouse; Rat; Predicted:Cow:PIG
Immunogen
Synthetic Peptide of PI 3 Kinase Class 3
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC
Validated Applications
WB,IHC
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
100kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8477-1.pdf
Observed Molecular Weight
100 kD
Subcellular Location
Other Product Names
Phosphoinositide-3-kinase, class 3
Gene ID (Human)
5289
SwissProt (Human)
Q8NEB9
Available Sizes
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