E-Selectin rabbit pAb
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
selectin E
Gene ID
6401
UniProt
P16581
Cellular Locus
Cell membrane ; Single-pass type I membrane protein.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SELE. AA range:100-150
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Molecular Weight
66kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8463-1.pdf
Observed Molecular Weight
66 kD
Subcellular Location
Cell membrane ; Single-pass type I membrane protein.
Other Product Names
Selectin E
Gene ID (Human)
6401
SwissProt (Human)
P16581
Available Sizes
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