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Vimentin (Phospho-Tyr38) rabbit pAb

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract. [provided by RefSeq, Jun 2009],

Product Specifications

Background

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

Product Name Alternative

VIM

UniProt

P08670

Swiss Prot

P08670

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)

Target

Vimentin

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB: 1:500-10000 ELISA: 1:10000

Buffer

-20°C/1 year

Molecular Weight

51kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

51kD

Fragment

IgG

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .

Other Product Names

VIM

Gene ID (Human)

7431

Available Sizes

Curated Selection

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