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Acetyl-EPAS-1 (K385) rabbit pAb

Endothelial PAS domain protein 1 (EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],

Product Specifications

Background

Endothelial PAS domain protein 1 (EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

UniProt

Q99814

Swiss Prot

Q99814

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized acetyl-peptide of Acetyl-EPAS-1 (K385)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Molecular Weight

120kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

120kD

Fragment

IgG

Subcellular Location

Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. .

Other Product Names

Endothelial PAS domain protein 1

Gene ID (Human)

2034

Available Sizes

Curated Selection

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