Calretinin rabbit pAb
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],
Product Specifications
Background
UniProt
P22676
Swiss Prot
P22676
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from calbindin 2 at AA range: 191-240
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
32kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
32kD
Fragment
IgG
Subcellular Location
Nucleus, cytoplasm, cytosol, gap junction, neuron projection, terminal bouton, synapse
Other Product Names
Calretinin (CR;29 kDa calbindin)
Gene ID (Human)
794
Available Sizes
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