AMPA receptor modulator-3
AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM) . AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2].
Product Specifications
CAS Number
211311-39-6
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ampa-receptor-modulator-3.html
Purity
99.57
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC(S(=O)(NCC(C1=CC=C(C2=CC=CC=C2F)C=C1)C)=O)C
Molecular Formula
C18H22FNO2S
Molecular Weight
335.44
References & Citations
[1]Kasper Harpsøe, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26 (5) :874-83. https://pubmed.ncbi.nlm.nih.gov/17644444/
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor
Available Sizes
Frequently Asked Questions
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