AMPA receptor modulator-3

AMPA receptor modulator-3 is an allosteric AMPA receptor modulator (EC50: 4.4 μM) . AMPA receptor modulator-3 can be used in the research of mammalian nervous system, such as learning and memory[1][2].

Product Specifications

CAS Number

[211311-39-6]

UNSPSC

12352005

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ampa-receptor-modulator-3.html

Purity

99.57

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC(S(=O)(NCC(C1=CC=C(C2=CC=CC=C2F)C=C1)C)=O)C

Molecular Formula

C18H22FNO2S

Molecular Weight

335.44

References & Citations

[1]Kasper Harpsøe, et al. Prediction of the binding mode of biarylpropylsulfonamide allosteric AMPA receptor modulators based on docking, GRID molecular interaction fields and 3D-QSAR analysis. J Mol Graph Model. 2008 Jan;26 (5) :874-83. https://pubmed.ncbi.nlm.nih.gov/17644444/