BMP-2 rabbit pAb
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016],
Product Specifications
Background
Synonyms
BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
Gene ID
650
UniProt
P12643
Cellular Locus
Secreted.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from Bone morphogenetic protein 2 at AA range: 341-390
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
IF, WB, IHC, ELISA
Validated Applications
IF,WB,IHC,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
44kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8416-1.pdf
Observed Molecular Weight
44 kD
Subcellular Location
Secreted.
Other Product Names
BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A
Gene ID (Human)
650
SwissProt (Human)
P12643
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
