IL-1F10 rabbit pAb

The protein encoded by this gene is a member of the interleukin 1 Cytokine family. This gene and eight other interleukin 1 family genes form a Cytokine gene cluster on chromosome 2. This Cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

UniProt

Q8WWZ1

Swiss Prot

Q8WWZ1

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from Interleukin-1 family member 10 at AA range: 101-150

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

17kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

17kD

Fragment

IgG

Subcellular Location

Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .