HTMT (dimaleate)

HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells[1].

Product Specifications

CAS Number

[195867-54-0]

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/htmt-dimaleate.html

Purity

99.55

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC(NCCC1=CN=CN1)CCCCC(NC2=CC=C(C(F)(F)F)C=C2)=O.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O

Molecular Formula

C27H33F3N4O9

Molecular Weight

614.57

References & Citations

[1]Khan MM, Marr-Leisy D, Verlander MS, Bristow MR, Strober S, Goodman M, Melmon KL. The effects of derivatives of histamine on natural suppressor cells. J Immunol. 1986 Jul 1;137 (1) :308-14.