APP-BP2 rabbit pAb
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. The encoded protein may be involved in regulating cell death. This gene has been found to be highly expressed in breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Product Specifications
Background
Synonyms
Gene ID
10513
UniProt
Q92624
Cellular Locus
Nucleus. Cytoplasm, cytoskeleton. Membrane ; Peripheral membrane protein. Associated with membranes and microtubules..
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from APP-BP2 . at AA range: 390-470
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
67kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8357-1.pdf
Observed Molecular Weight
67 kD
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton . Membrane ; Peripheral membrane protein . Associated with membranes and microtubules. .
Other Product Names
Gene ID (Human)
10513
SwissProt (Human)
Q92624
Available Sizes
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