Cdc25C (phospho Thr48) rabbit pAb
Cell division cycle 25C (CDC25C) Homo sapiens This gene encodes a conserved protein that plays a key role in the regulation of cell division. The encoded protein directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It also suppresses p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Dec 2015],
Product Specifications
Background
Synonyms
CDC25C; M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C
Gene ID
995
UniProt
P30307
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Rat,Mouse,
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CDC25C around the phosphorylation site of Thr48. AA range:14-63
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
80kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8143-1.pdf
Observed Molecular Weight
80 kD
Subcellular Location
Nucleus .
Other Product Names
CDC25C; M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C
Gene ID (Human)
995
SwissProt (Human)
P30307
Available Sizes
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