Cdc25A (phospho Ser75) rabbit pAb
Cell division cycle 25A (CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
Gene ID
993
UniProt
P30304
Cellular Locus
Intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CDC25A around the phosphorylation site of Ser75. AA range:43-92
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, ELISA
Validated Applications
WB,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
60kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8127-1.pdf
Observed Molecular Weight
60 kD
Subcellular Location
Intracellular, nucleus, nucleoplasm, cytoplasm, cytosol
Other Product Names
CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
Gene ID (Human)
993
SwissProt (Human)
P30304
Available Sizes
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