N-CoR rabbit pAb
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [provided by RefSeq, Jun 2010],
Product Specifications
Background
Synonyms
NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
Gene ID
9611
UniProt
O75376
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human NCoR1. AA range:51-100
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
270kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES8074-1.pdf
Observed Molecular Weight
270 kD
Subcellular Location
Nucleus .
Other Product Names
NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
Gene ID (Human)
9611
SwissProt (Human)
O75376
Available Sizes
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