What is the catalog number for HAND1 rabbit pAb?

The catalog number for HAND1 rabbit pAb is ES8040.

What sizes are available for HAND1 rabbit pAb?

HAND1 rabbit pAb is available in the following size(s): 50 µL, 100 µL.

How many pack sizes does HAND1 rabbit pAb come in?

HAND1 rabbit pAb is available in 2 different pack sizes.

Is HAND1 rabbit pAb in stock?

HAND1 rabbit pAb is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HAND1 rabbit pAb?

HAND1 rabbit pAb is manufactured by ELK.

What is the estimated delivery time for HAND1 rabbit pAb?

Estimated delivery time for HAND1 rabbit pAb is approximately 10 business day(s), depending on your location.

HAND1 rabbit pAb

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Product Name Alternative

HAND1; BHLHA27; EHAND; Heart- and neural crest derivatives-expressed protein 1; Class A basic helix-loop-helix protein 27; bHLHa27; Extraembryonic tissues; heart, autonomic nervous system and neural crest derivatives-expressed protein 1; eH

UniProt

O96004

Swiss Prot

O96004

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human HAND1. AA range:141-190

Target

HAND1

Clonality

Polyclonal

Source

Rabbit

Applications

IF; ELISA

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Nucleus, nucleoplasm . Nucleus, nucleolus . Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to transcription factor activity (By similarity) . .