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Rab 11B rabbit pAb

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al. 1994 [PubMed 7811277]). [supplied by OMIM, Nov 2010],

Product Specifications

Background

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]) .[supplied by OMIM, Nov 2010]

Synonyms

RAB11B; YPT3; Ras-related protein Rab-11B; GTP-binding protein YPT3

Gene ID

9230

UniProt

Q15907

Cellular Locus

Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side. Recruited to phagosomes containing S.aureus..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RAB11B. AA range:164-213

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB, IHC

Validated Applications

WB,IHC

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:500-2000; IHC-p 1:50-300

Molecular Weight

28kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7996-1.pdf

Observed Molecular Weight

28 kD

Subcellular Location

Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome membrane ; Lipid-anchor ; Cytoplasmic side . Recruited to phagosomes containing S.aureus. .

Other Product Names

RAB11B; YPT3; Ras-related protein Rab-11B; GTP-binding protein YPT3

Gene ID (Human)

9230

SwissProt (Human)

Q15907

Available Sizes

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