Taurine-13C2

Taurine-13C2 is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

Product Specifications

CAS Number

[70155-54-3]

Product Name Alternative

2-Aminoethanesulfonic acid-13C2

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Autophagy; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/taurine-13c2.html

Purity

99.0

Solubility

H2O : 25 mg/mL (ultrasonic; warming)

Smiles

N[13CH2][13CH2]S(=O)(O)=O

Molecular Formula

13C2H7NO3S

Molecular Weight

127.13

Precautions

H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Ripps H, Shen W. Review: taurine: a "very essential" amino acid. Mol Vis. 2012;18:2673-2686.|[3]Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13 (2) :57-65.|[4]Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50 (5) :527-535.