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NCKX1 rabbit pAb

This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Product Specifications

Background

This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Product Name Alternative

SLC24A1; KIAA0702; NCKX1; Sodium/potassium/calcium exchanger 1; Na (+) /K (+) /Ca (2+) -exchange protein 1; Retinal rod Na-Ca+K exchanger

UniProt

O60721

Swiss Prot

O60721

Reactivity

Human; Rat; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human SLC24A1. AA range:154-203

Target

NCKX1

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Buffer

-20°C/1 year

Molecular Weight

125kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

125kD

Fragment

IgG

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

Other Product Names

SLC24A1; KIAA0702; NCKX1; Sodium/potassium/calcium exchanger 1; Na (+) /K (+) /Ca (2+) -exchange protein 1; Retinal rod Na-Ca+K exchanger

Gene ID (Human)

9187

Available Sizes

Curated Selection

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