Claudin-10 rabbit pAb
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined. [provided by RefSeq, Jun 2010],
Product Specifications
Background
Synonyms
CLDN10; Claudin-10; OSP-like protein
Gene ID
9071
UniProt
P78369
Cellular Locus
Cell junction, tight junction. Cell membrane ; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Claudin 10. AA range:179-228
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB, IHC, IF, ELISA
Validated Applications
WB,IHC,IF,ELISA
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
Molecular Weight
25kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7948-1.pdf
Observed Molecular Weight
25 kD
Subcellular Location
Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .
Other Product Names
CLDN10; Claudin-10; OSP-like protein
Gene ID (Human)
9071
SwissProt (Human)
P78369
Available Sizes
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