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STAM2 (phospho Tyr192) rabbit pAb

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of Cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to Cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon Cytokine stimulation. [provided by RefSeq, Jul 2008],

Product Specifications

Background

The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM) . Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation. [provided by RefSeq, Jul 2008]

UniProt

O75886

Swiss Prot

O75886

Reactivity

Human; Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human STAM2 around the phosphorylation site of Tyr192. AA range:161-210

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC; IF; ELISA

Concentration

1 mg/ml

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight

58kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

58kD

Fragment

IgG

Subcellular Location

Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .

Other Product Names

STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein

Gene ID (Human)

8986

Available Sizes

Curated Selection

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