STAM2 (phospho Tyr192) rabbit pAb
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of Cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to Cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon Cytokine stimulation. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
O75886
Swiss Prot
O75886
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human STAM2 around the phosphorylation site of Tyr192. AA range:161-210
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES7923-1.pdf
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side .
Other Product Names
STAM2; HBP; Signal transducing adapter molecule 2; STAM-2; Hrs-binding protein
Gene ID (Human)
8986
Available Sizes
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